Detection of Toscana virus-specific immunoglobulins G and M by an enzyme-linked immunosorbent assay based on recombinant viral nucleoprotein.

نویسندگان

  • M G Ciufolini
  • C Fiorentini
  • P di Bonito
  • S Mochi
  • C Giorgi
چکیده

An enzyme-linked immunosorbent assay (ELISA) based on the recombinant Toscana virus nucleoprotein (rN) has been developed. Its sensitivity and specificity for the detection of virus-specific immunoglobulins G and M in human sera were similar to those of the ELISA that is based on an antigen extracted from infected mouse brain and that is routinely used for serodiagnosis.

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عنوان ژورنال:
  • Journal of clinical microbiology

دوره 37 6  شماره 

صفحات  -

تاریخ انتشار 1999